Most people with platelet function disorders only need treatment during surgical procedures (including dental work) and after injury or accidents.
Treatment
Bernard-Soulier syndrome
Most people with platelet function disorders only need treatment during surgical procedures (including dental work) and after injury or accidents. When needed, Bernard-Soulier syndrome may be treated with:
- Antifibrinolytic drugs e.g. tranexamic acid
- Recombinant factor VIIa
- Desmopressin (DDAVP)
- Fibrin sealants
- Hormonal contraceptives (to control excessive menstrual bleeding)
- Iron replacement (if necessary to treat anaemia caused by excessive or prolonged bleeding)
- Platelet transfusions (only if bleeding is severe)
People with inherited platelet function disorders should not take Aspirin®, nonsteroidal anti-inflammatory drugs (such as ibuprofen and naproxen), and blood thinners, which can make their bleeding symptoms worse.
Glanzmann thrombasthenia
Most people with platelet function disorders only need treatment during surgical procedures (including dental work) and after injury or accidents. When needed, Glanzmann thrombasthenia may be treated with:
- Antifibrinolytic drugs e.g. tranexamic acid
- Recombinant factor VIIa
- Fibrin sealants
- Hormonal contraceptives (to control excessive menstrual bleeding)
- Iron replacement (if necessary to treat anaemia caused by excessive or prolonged bleeding)
- Platelet transfusions (only if bleeding is severe)
People with inherited platelet function disorders should not take Aspirin®,nonsteroidal anti-inflammatory drugs (such as ibuprofen and naproxen), and blood thinners, which can make their bleeding symptoms worse.
Storage pool deficiencies
Most people with storage pool deficiencies only need treatment during surgical procedures (including dental work) and after injury or trauma. When needed, storage pool deficiencies may be treated with:
- Antifibrinolytic drugs e.g. tranexamic acid
- Desmopressin (DDAVP) (may not be useful in alpha granule deficiency)
- Platelet transfusions
People with inherited platelet function disorders should not take Aspirin®,nonsteroidal anti-inflammatory drugs (such as ibuprofen and naproxen), and blood thinners, which can make their bleeding symptoms worse.
Content reproduced with permission from www.wfh.org
